Chimica Farmaceutica

Team Leader
SORBA Giovanni

Activity and fields of competence

1. Discovery of new anti-tubulin agents
2. Discovery of new PI3 kinase inhibitors
3. Discovery of new inhibitors of nicotinamide phosphoribosyl transferase
4. Discovery of new multicomponent reactions
5. Use of click chemistry in pharmaceutical chemistry
6. Use of molecular modelling techniques in pharmaceutical chemistry

Technological Resources

Different software packages are used to rationally design new ligands by working closely with synthetic chemists. Numerous techniques such as docking and virtual screening are used to explore ligand interactions and explore chemical space.

The group has extensive experience in the synthesis, manipulation and use of isonitriles and azides.

The laboratory uses synthetic organic chemistry techniques from microscale preparations up to multigram.

ERC Sector

LS7, PE4, PE5

Team Members

• TRON Gian Cesare
• PIRALI Tracey
• GALLI Ubaldina
• MASSAROTTI Alberto
• MERCALLI Valentina
• GRIGLIO Alessia
• SERAFINI MARTA, DSF, post-grad scholarship researcher